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Antioxidant support, Cellular protection, Vascular health
Adults with busy lifestyles seeking broad antioxidant support or those with low fruit and botanical polyphenol intake.
Take 2 tablets daily, preferably with food to be gentle on the stomach; products containing green tea extracts may be better tolerated earlier in the day if sensitive to caffeine.
Contains: Soy
Vitamin C donates electrons to neutralize free radicals and supports regeneration of other antioxidants in the body.
Caution: High doses may cause digestive discomfort; space away from iron supplements only if advised due to potential effects on iron absorption.
Resveratrols act as polyphenol antioxidants that may influence cell signaling pathways related to oxidative stress balance.
Caution: May interact with medications that affect blood clotting; discontinue before surgery as a precaution.
Green tea catechins act as antioxidants and may modulate cell signaling involved in oxidative stress.
Caution: Contains naturally occurring caffeine; may cause jitteriness or affect sleep if sensitive.
Proanthocyanidins in grape seed act as potent antioxidants that help stabilize free radicals and support vascular integrity.
Caution: May have mild blood-thinning effects; use caution with anticoagulant or antiplatelet drugs.
Pycnogenol provides procyanidins that scavenge reactive oxygen species and support nitric oxide balance in blood vessels.
Caution: May enhance effects of blood-thinning medications; monitor for bruising if combined.
Vitamin C helps regenerate and extend the activity of plant polyphenols, while resveratrols, grape seed proanthocyanidins, Pycnogenol procyanidins, and green tea catechins cover diverse antioxidant pathways. Together they address both water- and lipid-phase free radicals and support vascular and cellular redox balance.
Label Warning: Do not use if you are pregnant, may become pregnant, or breastfeeding. Do not use if you are taking anticoagulant drugs such as heparin or warfarin. May interfere with iron absorption; if you are anemic, take between meals. If you are taking any prescription drug, consult a physician before use.
Who should be cautious: People with soy allergy due to soy content. Those with bleeding concerns or scheduled surgery, and individuals on blood pressure or blood sugar medications may need extra caution due to ingredients like ginkgo, hawthorn, turmeric, and resveratrol. People with liver conditions should be cautious with milk thistle and green tea extracts. Those sensitive to caffeine should note green tea extract may contain small amounts. If taking medications, consult a healthcare provider before use.
Storage: Store in a cool, dry place.
Customers mention smoother-looking skin with fewer wrinkles and a brighter complexion.
Several users report feeling better overall with improved concentration and memory.
A few users say the tablets are big and not easy to swallow.
This product is guaranteed authentic and backed by our easy returns & refunds policy. Details
Both may support healthy circulation and skin health, offering antioxidant benefits that complement each other for overall wellness.
AI generated. Not medical advice.
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Pycnogenol® Supreme™ is a power-packed antioxidant complex featuring Pycnogenol®, a premium, scientifically- researched pine bark extract. This synergistic formula combines Pycnogenol® and a full 500 mg of vitamin C with more than 25 additional plant-derived antioxidants for the broad range of free radical protection recommended by many scientists. Together these compounds defend your tissues and cells from the oxidative stress that is so prevalent in today's environment.
2 tablets daily.
Silicified microcrystalline cellulose, stearic acid, modified cellulose gum, and silica.
Contains soy.
Do not use if you are pregnant, may become pregnant, breastfeeding, or taking anticoagulant drugs such as heparin or warfarin (Coumadin®). May interfere with the absorption of iron; if you are anemic, take between meals. If you are taking any prescription drug, consult a physician before using this product.
Do not use if either tamper-evident seal is broken or missing. Keep out of the reach of children.
Store in a cool, dry place.
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
| Supplement facts | ||
| Serving Size: 2 Tablets | ||
| Servings Per Container: 30 | ||
| Amount Per Serving | %DV | |
| Calories | 10 | |
| Total Carbohydrate | 1 g | <1%* |
| Vitamin C (as ascorbic acid) | 500 mg | 556% |
| Sodium | 5 mg | <1% |
| Polygonum cuspidatum Root Ext. (8% total resveratrols) | 200 mg | † |
| Green Tea Leaf Extract | 150 mg | † |
| Grape Seed Extract (Proanthodyn™) | 150 mg | † |
| Turmeric Rhizome | 100 mg | † |
| Rosemary Leaf Ext. | 100 mg | † |
| Lecithin | 100 mg | † |
| Bromelain | 100 mg | † |
| Quercetin | 95 mg | † |
| Ginkgo Leaf Ext. (24% flavone glycosides & 6% terpene lactones) | 60 mg | † |
| Rutin | 60 mg | † |
| French Maritime Pine Bark Extract (Pycnogenol®) (65% procyanidins) | 50 mg | † |
| Silymarin (from milk thistle seed extract) | 50 mg | † |
| Hawthorn Berry Extract | 50 mg | † |
| Citrus Bioflavonoid Complex | 50 mg | † |
| Astragalus Root Ext. | 50 mg | † |
| Cranberry Fruit | 50 mg | † |
| Sweet Cherry Fruit Ext. | 50 mg | † |
| Holy Basil Leaf Extract | 50 mg | † |
| Olive Leaf Extract (10% oleuropein) | 40 mg | † |
| Lycium Fruit Ext. | 40 mg | † |
| Strawberry Fruit | 40 mg | † |
| Acai Fruit Extract | 40 mg | † |
| Organic Amla Fruit | 40 mg | † |
| Pomegranate Fruit Ext. | 20 mg | † |
| Elderberry Fruit Ext. | 20 mg | † |
| Mangosteen Fruit Rind Ext. | 10 mg | † |
| Raspberry Leaf Ext. | 10 mg | † |
| Black Pepper Fruit Ext. (BioPerine®) | 6 mg | † |
| Bilberry Fruit Extract (32% anthocyanosides) | 5 mg | † |
| *Percent Daily Values (%DV) are based on a 2,000 calorie diet. †Daily Value not established. | ||
